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相关概念视频

Aging01:26

Aging

56
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
56
Circadian Rhythms and Gene Regulation02:19

Circadian Rhythms and Gene Regulation

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The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent...
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Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

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Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
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Introduction to Cognitive Psychology01:20

Introduction to Cognitive Psychology

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Cognitive psychology is the field of psychology dedicated to examining how people think. It attempts to explain how and why we think the way we do by studying the interactions among human thinking, emotion, creativity, language, and problem-solving, as well as other cognitive processes. Cognitive psychology studies how information is processed and manipulated in remembering, thinking, and knowing.
This field emerged in the mid-20th century, following a period dominated by behaviorism, which...
499
Revisionist Views of Adolescent and Adult Cognition01:24

Revisionist Views of Adolescent and Adult Cognition

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A revisionist approach to Jean Piaget's theory of cognitive development has brought new insights that challenge and reinterpret his established ideas. Piaget proposed that the formal operational stage, emerging in adolescence, represents the culmination of cognitive maturity. During this stage, individuals are said to develop abstract thinking, engage in systematic problem-solving, and show a form of egocentrism, believing others are as preoccupied with their behavior as they are...
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Automated, Long-term Behavioral Assay for Cognitive Functions in Multiple Genetic Models of Alzheimer's Disease, Using IntelliCage
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在老化的时钟模型中,可解释的人工智能 (XAI).

Alena Kalyakulina1, Igor Yusipov1, Alexey Moskalev2

  • 1Institute of Biogerontology, Lobachevsky State University, Nizhny Novgorod 603022, Russia; Research Center for Trusted Artificial Intelligence, The Ivannikov Institute for System Programming of the Russian Academy of Sciences, Moscow 109004, Russia; Department of Applied Mathematics, Institute of Information Technologies, Mathematics and Mechanics, Lobachevsky State University, Nizhny Novgorod 603022, Russia.

Ageing research reviews
|November 29, 2023
PubMed
概括
此摘要是机器生成的。

可解释性AI (XAI) 对于理解复杂的机器学习模型至关重要,特别是在医疗保健和衰老研究中. 本综述探讨了XAI在开发老化时钟和分析生理系统数据中的应用.

关键词:
与年龄有关的疾病与年龄有关的疾病.衰老的衰老 衰老的衰老可解释的人工智能长寿 长寿是一个问题.机器学习 机器学习

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科学领域:

  • 机器学习 机器学习
  • 人工智能的人工智能
  • 老年学是一门学科.

背景情况:

  • 可解释性AI (XAI) 对于解释复杂的机器学习模型至关重要.
  • 在医疗保健等敏感领域,XAI对于人工智能驱动的决策至关重要.
  • 人工智能越来越多地用于生物钟和生物标志物发现的衰老研究.

研究的目的:

  • 探索XAI在开发老化的钟表中的应用.
  • 提供关于XAI在衰老研究中的综合文献分析.
  • 根据生理系统对XAI应用进行分类.

主要方法:

  • 文献审查和分析.
  • 基于生理系统的研究分类.
  • 讨论XAI在老化时钟开发中的作用.

主要成果:

  • 在衰老研究中XAI的潜力是显著的,但未被充分探索.
  • 在各种生理系统中,XAI的应用是多样化的.
  • 介绍了XAI在老化时钟开发中的结构化概述.

结论:

  • 对于推进衰老研究和了解生物衰老,XAI具有很大的前景.
  • 需要进一步的研究,以充分利用XAI来强大的衰老生物标志物和时钟.
  • 系统地应用XAI可以提高AI在衰老研究中的可靠性.