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Updated: Jul 9, 2025

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葡萄糖皮质体受体 (GR) 激活与割抗性前列腺癌中增加的cAMP/PKA信号相关

Lynda Bennett1, Praveen Kumar Jaiswal1, Ryan V Harkless1

  • 1Division of Hematology and Oncology, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, Texas.

Molecular cancer therapeutics
|November 29, 2023
PubMed
概括

在抵抗割的前列腺癌中,葡萄糖皮质体受体 (GR) 活性驱动循环腺单酸盐 (cAMP) 信号传递. 通过选择性调制剂和雄激素受体对抗剂一起抑制GR,可以通过向这种途径来延缓癌症的进展.

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