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卵巢刺激期间的SARS-CoV-2感染对ART结果的影响

Tianjin Yang¹, Longmei Wu², Jing Peng¹

¹Department of Obstetrics and Gynaecology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.

Reproductive biomedicine online

|November 29, 2023

概括

在卵巢刺激期间严重急性呼吸道综合征冠状病毒-2 (SARS-CoV-2) 感染不会影响体外受精 (IVF) 的结果. 在这项研究中,COVID-19并没有对生殖系统构成风险.

科学领域:

生殖医学生殖医学
传染性疾病传染性疾病
在体外受精 (IVF)

背景情况:

SARS-CoV-2 感染对辅助生殖技术 (ART) 结果的影响仍然是不孕症患者的担忧.
了解卵巢刺激期间COVID-19的影响对于指导治疗决策至关重要.

研究的目的:

评估卵巢刺激期间急性SARS-CoV-2感染对试管婴儿治疗结果的影响.
在接受试管婴儿的患者中评估COVID-19对生殖系统的潜在风险.

主要方法:

追溯队列研究将151个试管婴儿周期与刺激期间的COVID-19与224个控制周期进行比较.
分析临床特征和实验室参数,包括卵细胞检索,受精率和胚胎细胞发育.
对毛囊液,精液和胚胎培养基进行RT-PCR检测,以检测SARS-CoV-2 RNA.

主要成果:

在受感染和对照组之间,在周期特征,卵细胞产量,受精率或胚胎胚胎可用性方面没有发现显著差异.
从COVID-19阳性患者的任何测试生物样本中没有检测到SARS-CoV-2RNA.
无论急性SARS-CoV-2感染状况如何,卵巢刺激和试管婴儿的结果都是可比的.

结论:

在卵巢刺激期间急性SARS-CoV-2感染不会显著影响试管婴儿治疗结果.
在SARS-CoV-2感染的患者中没有观察到生殖系统风险的证据.
患有轻度或无症状COVID-19的个人可以安全地继续进行试管婴儿治疗.

关键词:

排卵刺激刺激的排卵.生殖技术生殖技术这就是SARS-CoV-2病毒.

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