空气污染暴露对心脏代谢风险因素的影响:一篇综述
Li-Hao Guo1, Mohammed Zeeshan1, Guo-Feng Huang2
1Guangdong Provincial Engineering Technology Research Center of Environmental Pollution and Health Risk Assessment, Department of Occupational and Environmental Health, School of Public Health, Sun Yat-Sen University, 74 Zhongshan 2Nd Road, Yuexiu District, Guangzhou, 510080, China.
空气污染暴露与糖尿病和高血压等心脏代谢风险因素 (CRF) 有关. 了解这种联系对于公共卫生和开发针对心血管疾病的干预措施至关重要.
科学领域:
- 环境健康 环境健康
- 心血管医学 心血管医学
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 心脏代谢风险因素 (CRF) 正在增加,推动心血管疾病的流行.
- 空气污染是与CRF发展和严重程度相关的重大环境健康危害.
研究的目的:
- 审查有关各种空气污染物和CRF之间的关系的当前研究.
- 总结最近关于空气污染对心血管和代谢健康的影响的发现.
主要方法:
- 对人口流行病学研究的审查.
- 分析利用新的生物监测指标和生物标志物的研究.
主要成果:
- 空气污染暴露和CRF之间始终显示出正相关性.
- 关键机制包括氧化应激,炎症和内皮功能障碍.
- 生物标志物的异常如homocysteine,尿酸和C反应性蛋白被注意到.
结论:
- 空气污染对CRF的发展和进展作出了重大贡献.
- 需要进一步的研究来探索新的CRF生物标志物,并开发有针对性的干预措施.
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