意识障碍的共同数据元素:治疗干预工作组的建议
Martin M Monti1, Rachel Beekman2, Norman M Spivak3
1Department of Psychology, University of California Los Angeles, 6522 Pritzker Hall, Los Angeles, CA, USA. monti@psych.ucla.edu.
Neurocritical care
|November 29, 2023
概括
研究人员开发了一种标准化的病例报告表格,以改善对意识障碍的新型治疗干预措施的评估. 这旨在加强报告和系统化未来的研究,以恢复大脑损伤后的意识.
科学领域:
- 神经科学是一个神经科学.
- 临床研究方法论 临床研究方法论
背景情况:
- 在了解脑损伤后的意识丧失和恢复方面取得了重大进展.
- 需要对新型治疗干预措施进行标准化报告.
- 由于技术的多样性和缺乏严格的试验,评估干预措施的挑战.
研究的目的:
- 开发用于治疗干预的共同数据元素 (CDE).
- 为研究意识障碍创建一个标准化的病例报告表 (CRF).
主要方法:
- 审查了现有的CDE和相关文献.
- 代地提出,讨论和审查CDE.
- 组织CDE成一个结构化的CRF.
主要成果:
- 开发了一个统一的CRF与CDE和关键设计元素.
- CRF分为五个部分:患者信息,一般研究信息,行为干预,药理干预和设备干预.
结论:
- 新的CRF系统化了对意识障碍干预措施的未来研究.
- 为评估新型意识恢复疗法的研究提供了一系列措施.
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