托芬缓解慢性热应激引起的抗氧化能力,炎症反应和肉中的线粒体功能受损
Jingxin Ouyang1,2, Qiufen Li1,2, Hua Zhou1,2
1Jiangxi Province Key Laboratory of Animal Nutrition, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, 330045, China.
Tropical animal health and production
|November 29, 2023
概括
食托补充剂改善了热应激肉的抗氧化能力和线粒体功能. 这种营养策略有效地减少了炎症,并防止了与热应激相关的损伤.
科学领域:
- 动物科学动物科学
- 营养生物化学 营养生物化学
- 禽类生理学 禽类生理学
背景情况:
- 热应激 (HS) 对肉健康产生负面影响,导致氧化应激和炎症.
- 线粒体功能受损是禽类热应激的一个关键后果.
- 需要饮食策略来减轻热应激对 brojlers 的不利影响.
研究的目的:
- 为了研究食中托 (Trp) 补充剂对热应激下 brojlers 的影响.
- 评估Trp对血清生物化学和抗氧化剂指数,细胞因子水平和线粒体功能的影响.
- 评估Trp在改善热应激肉中线粒体形态和基因表达中的作用.
主要方法:
- 180个Arbor Acres肉被分为热中性 (TN) 和热应激 (HS) 组.
- 在21天的时间里,HS组接受了基底饮食,并补充了0%或0.18%的Trp.
- 分析了血清生物化学指数,抗氧化剂状况,细胞因子水平和叶线粒体基因表达.
主要成果:
- 热应激降低了血清总蛋白和抗氧化酶活动,同时增加了促炎性细胞因子.
- 托芬补充剂 (0.18%) 增强了抗氧化能力,降低了肝酶,降低了炎症性细胞因子水平.
- 饮食Trp改善了线粒体膜潜力,上调了关键线粒体基因表达 (TFAM,COX1),并改善了线粒体损伤.
结论:
- 食托补充剂有效地改善了热应激肉的抗氧化能力和线粒体功能.
- 补充Trp有助于调节与线粒体功能相关的基因,并减少炎症反应.
- 托是一种有前途的营养策略,可以保护肉免受热应激损害.
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