在慢性阻塞性肺病患者中,伴随性疾病和死亡风险的性别差异:基于NHANES数据的研究
Na Li1, Xiaoli Li1, Minjie Liu1
1Department of Respiratory, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, 710054, People's Republic of China.
与女性相比,患有慢性阻塞性肺病 (COPD) 的男性的生存率较低,并具有不同的并发症概况. 这项研究强调了COPD结果和相关疾病的显著性别差异.
科学领域:
- 肺部医学 肺部医学
- 流行病学 流行病学
- 健康中的性别差异
背景情况:
- 慢性阻塞性肺病 (COPD) 患者经常有并发症,使结果恶化.
- 关于COPD患者共发病率分布和死亡率的性别差异的研究有限.
- 了解这些差异对于有针对性的患者护理和公共卫生战略至关重要.
研究的目的:
- 为了调查COPD患者的并发症患病率的性别差异.
- 分析性对COPD患者全因死亡率的影响.
- 确定与COPD男性和女性死亡风险增加相关的特定并发症.
主要方法:
- 利用美国国家健康和营养检查调查 (2007-2012) 的数据.
- 包括40-79岁的参与者,患有螺旋计定义的COPD.
- 采用Kaplan-Meier生存分析和Cox相称风险模型,以按性别分层的并发症-死亡率关联.
主要成果:
- 与男性相比,患有COPD的女性患喘和关节炎的患病率更高.
- 患有COPD的男性患冠心病和痛风的患病率高于女性.
- 男性的生存率明显低于女性 (p < 0.001). 贫血,痛风和充血性心力衰竭增加了男性的死亡风险;贫血和中风增加了女性的死亡风险.
结论:
- 在COPD患者的并发症模式和全因死亡率中存在显著的性别差异.
- 与女性相比,患有COPD的男性的生存结果较差.
- 在COPD患者群体中,特定的并发症对性别之间的死亡风险产生不同影响.
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