Acinetobacter baumannii:在黎巴嫩的一家高等教学医院评估易感性模式,管理实践和死亡率预测因素
Rania Itani1, Hani M J Khojah2, Samar Karout3
1Pharmacy Practice Department, Faculty of Pharmacy, Beirut Arab University, Riad El Solh, 1107 2809, P.O. Box: 11-5020, Beirut, Lebanon.
Antimicrobial resistance and infection control
|November 30, 2023
概括
菌感染导致高死亡率,近一半的患者接受不适当的初始抗生素治疗. 不适当的治疗,机械通风和血小板狭窄症显著增加了这些患者的死亡风险.
科学领域:
- 传染性疾病 传染性疾病
- 临床微生物学 临床微生物学
- 临界护理医学 临界护理医学
背景情况:
- 宝曼尼菌 (Acinetobacter baumannii) 是医院感染的重要原因之一.
- 这种病原体表现出高水平的抗生素耐药性,导致患者的治疗结果不佳.
- A. baumannii感染与相当高的死亡率有关.
研究的目的:
- 为了评估A. baumannii. 的抗菌敏感性模式.
- 评估A. baumannii感染的初始抗菌疗法的适当性.
- 确定死亡率,并确定感染患者死亡率的预测因素.
主要方法:
- 对患有A. baumannii感染的患者进行了回顾性观察研究.
- 对抗菌素敏感性和治疗适当性的医疗记录的分析.
- 卡普兰-梅尔生存分析和二元逻辑回归用于死亡率预测.
主要成果:
- 观察到对碳烯的高耐药率和广泛的耐药性.
- 几乎一半 (45.1%) 的患者接受了不适当的初始抗菌药物治疗.
- 30天死亡率为71.2%,不适当的治疗,机械通风和血小板狭窄是死亡率的重要预测因素.
结论:
- A. baumannii感染与高而令人担忧的死亡率有关.
- 不适当的抗菌药物治疗,机械通风和血小板缺血是死亡率的关键预测因素.
- 及时,适当的抗微生物治疗,以及感染控制和管理,对于改善结果至关重要.
关键词:
这种细菌是Acinetobacter baumannii.抗生素 抗生素是一种抗生素.黎巴嫩 黎巴嫩 黎巴嫩 黎巴嫩 黎巴嫩 黎巴嫩死亡率 死亡率 死亡率多种药物耐药性多种药物耐药性风险因素 风险因素易感性模式的模式治疗结果的结果.更多相关视频
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