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来自植物的天然化合物作为新兴的抗病毒药物,用于打击COVID-19

Mansi Singh¹, Shih-Hsiu Lo², Rajni Dubey³

¹Department of Pharmacy, Institute of Pharmaceutical Research, GLA University, Mathura, UP 281406 India.

Indian journal of microbiology

|November 30, 2023

概括

草药植物和植物化学物质显示出对抗SARS-CoV-2 (COVID-19) 的承诺. 纳米配方通过改善对病毒的传递和有效性来增强其抗病毒特性.

科学领域:

植物化学植物化学
病毒学病毒学
纳米技术纳米技术

背景情况:

严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 导致全球大流行,数百万人死亡.
病毒继续演变为新的突变菌株.
传统的治疗方法补充了对自然化合物的研究.

研究的目的:

审查草本植物和植物化学品对抗SARS-CoV-2的潜力.
探索这些天然化合物发挥抗病毒作用的机制.
突出纳米配方在增强治疗疗效方面的作用.

主要方法:

文献综述重点关注与SARS-CoV-2相关的草药,植物化学品和纳米技术.
对研究植物化合物的抗炎和免疫调节性质的研究进行分析.
对纳米配方植物化学品的研究进行审查,以提高生物可用性和有针对性的输送.

主要成果:

草药和香料具有抗炎和免疫调节性质,对病毒感染有益.
植物化学品的纳米配方证明了对SARS-CoV-2的潜在治疗效果.
来自植物的纳米配方通过增强生物可用性,溶解性和输送来改善抗病毒活性.

结论:

草药化合物为SARS-CoV-2治疗提供了一个有希望的途径.
纳米配方显著提高了植物化学品的抗病毒潜力.
机制包括阻断ACE-2受体,抑制蛋白酶,结合尖端蛋白,减少细胞因子风暴.

关键词:

草本植物是草本植物.纳米配方纳米配方纳米配方植物化学品植物化学品这就是SARS-CoV-2病毒.

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