在运动期间患有创伤后应激障碍的女性中,外周氧气提取减弱和心脏输出增加
Andrew W D'Souza1,2,3, Jeung-Ki Yoo2,3, Salman Bhai2,4
1Neurovascular Research Laboratory, School of Kinesiology, Western University, London, Ontario, Canada.
Journal of applied physiology (Bethesda, Md. : 1985)
|November 30, 2023
概括
患有创伤后应激障碍 (PTSD) 的女性没有较低的最大氧气摄入量 (V·o2max),但在运动期间显示氧气使用受损. 运动期间和运动后心血管反应在患有PTSD的女性中发生变化.
科学领域:
- 心血管生理学心血管生理学
- 运动科学 运动科学
- 心理生理学 心理生理学
背景情况:
- 创伤后应激障碍 (PTSD) 与心血管疾病有关,特别是在女性中.
- 患有创伤后应激障碍的男性最大氧气吸收量有所降低 (V·o2max),但这在女性中尚未研究.
- 在患有PTSD的女性中,影响Vo2max的中心和外围因素尚不清楚.
研究的目的:
- 在患有PTSD的女性中调查Vo2max及其决定因素 (心脏输出和动脉静脉氧差).
- 为了比较PTSD和没有PTSD的女性在最大限度的运动期间的心血管反应.
- 探索运动后自主心血管控制的潜在差异.
主要方法:
- 在增量跑步机运动期间测量Vo2max,心脏输出量 (Q̇c),中风体积 (SV),心率 (HR) 和动脉静脉氧气差异.
- 包括14名患有PTSD的女性和17名健康对照.
- 计算了Q̇c/V̇o2的斜率,并评估了运动后的心率恢复.
主要成果:
- 在患有PTSD的女性和对照人群 (24.3与26.4毫升/千克/分钟) 之间,Vo2max是相似的.
- 患有PTSD的女性在运动期间表现出更高的QQ (由SV驱动) 和较低的动脉静脉氧差异.
- 患有PTSD的女性在运动后表现出更的Q̇c/V̇o2斜率和更慢的心率恢复.
结论:
- 尽管由于心脏输出增加,外周氧气提取减少,但PTSD女性的Vo2max仍然保持.
- 患有PTSD的女性在运动期间和运动后立即表现出心血管调节的改变.
- 这些发现表明,在患有PTSD的女性中,异常的心血管适应运动压力.
相关概念视频
Exercise and Cardiac Output
1.1K
Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
Sustained exercise increases the muscles' oxygen demand, which can be...
Sustained exercise increases the muscles' oxygen demand, which can be...
1.1K
Exercise Stress Test
234
Introduction
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
234
Exercise and Cardiovascular Response
826
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
826
Post-traumatic Stress Disorder
35
Post-traumatic stress disorder (PTSD) is a psychiatric condition that arises following exposure to traumatic events such as natural disasters, forced displacement, or severe accidents. It significantly impairs individuals' ability to cope with daily activities and disrupts their emotional and psychological equilibrium.
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events,...
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events,...
35
Introduction to Stress and Lifestyle
118
Stress is a multifaceted response to events perceived as challenging or threatening, highlighting physical, emotional, cognitive, and behavioral reactions. Physically, stress can lead to fatigue, sleep disruptions, and various health issues such as frequent colds, chest pains, and nausea. Emotionally, it can manifest as anxiety, depression, irritability, and anger triggered by both minor and major life events. Cognitively, it may result in difficulty in concentration, memory, and...
118
Psychoneuroimmunology: Cardiovascular Disease
31
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
A key area of focus in PNI is the relationship between stress and coronary...
31


