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在患有头癌的患者中,萨科佩尼亚的危险因素
Chen Liu1,2, Ling Cheng1,3, Wenfeng Ye2
1Department of Oncology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Head & neck
|November 30, 2023
概括
皮症影响18.6%的头癌患者. 男性性别,年龄较大,体脂较高会增加风险,而较高的BMI和体液/无脂肪总体质量则会提供保护.
科学领域:
- 在瘤学瘤学.
- 老年病的医生 老年病的医生
- 营养科学 营养科学
背景情况:
- 麻症是癌症患者中普遍存在的疾病,影响治疗结果和生活质量.
- 了解肉类的患病率和头癌 (HNC) 的风险因素对于开发有针对性的干预措施至关重要.
研究的目的:
- 为了确定头癌 (HNC) 患者中肉类的患病率.
- 确定与HNC患者的肉症相关的独立风险因素和保护因素.
- 建立一个基础,为未来的麻症预防和治疗策略在HNC.
主要方法:
- 一项涉及617名HNC患者的横截面观察性研究.
- 使用生物电阻分析 (BIA) 评估了骨肌肉质量.
- Sarcopenia 诊断遵循了 2019 年亚洲 Sarcopenia 工作组 (AWGS) 的标准,并进行了逻辑回归分析以确定风险因素.
主要成果:
- 麻症的患病率为18.6% (617名患者中有115名).
- 与女性 (8%) 相比,男性 (29.1%) 的患病率显著更高.
- 独立的危险因素包括年龄较大 (OR=12.266),体脂较高 (OR=1.775),男性性别 (OR=138.659).
- 保护因素是较高的身体质量指数 (BMI) (OR=0.137) 和总体水/无脂肪质量 (TBW/FFM) (OR=0.122).
结论:
- 男性性别,晚年和多余的身体脂肪是HNC患者肉症的重要危险因素.
- 较高的BMI和TBW/FFM与这种人群中 Sarcopenia 的风险降低有关.
- 这些发现有助于在头癌护理中制定针对人性化的沙科佩尼亚管理策略.
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