发育编程肥胖:抗炎营养策略有没有作用?
Michelle L Kearns1, Clare M Reynolds1
1Conway Institute/School of Public Health Physiotherapy and Sports Science/Institute of Food and Health/Diabetes Complications Research Centre, University College Dublin, Dublin 4, Ireland.
Experimental physiology
|November 30, 2023
概括
怀孕期间母亲的营养显著影响脂肪组织的发育,影响母亲和孩子未来的代谢健康. 个性化营养干预可以预防长期肥胖和相关疾病.
科学领域:
- 生殖生物学 生殖生物学
- 代谢健康 代谢健康
- 营养科学 营养科学
背景情况:
- 怀孕涉及重要的母亲生理适应,包括脂肪组织的变化,脂质代谢和胰岛素抵抗,以支持胎儿的生长.
- 孕妇的超重和肥胖增加了对妊娠期糖尿病等并发症的易感性,这种并发症影响到60%的欧洲女性.
- 怀孕期间母亲的营养不良可能导致母亲和孩子的长期代谢疾病倾向,强调怀孕是卫生干预的关键窗口.
研究的目的:
- 审查影响脂肪组织发育的子宫内因素.
- 检查这些因素对晚年肥胖和代谢健康的影响.
- 评估怀孕期间和生命早期的抗炎营养干预措施的治疗潜力.
主要方法:
- 关于怀孕期间母亲生理适应的研究文献综述.
- 分析脂肪组织发育在对子宫内因素的反应中的作用.
- 对预防晚年代谢疾病的饮食干预措施的证据的审查.
主要成果:
- 怀孕期间母亲的生理变化,特别是脂肪组织的变化,对于胎儿的发育至关重要.
- 超重/肥胖和怀孕期间的营养不足与妊娠糖尿病和晚年代谢障碍的风险增加有关.
- 怀孕期间和生命早期的营养干预有望减轻长期负面健康结果.
结论:
- 怀孕期间的孕产妇健康和营养是影响母亲和子女未来健康轨迹的关键窗口.
- 个性化的营养方法,考虑到个体对饮食策略的反应,对于预防肥胖和代谢综合征至关重要.
- 了解脂肪组织发育机制是为未来几代人开发有效干预措施的关键.
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