在患有原发性甲状腺功能增强症的狗中血清胃素度
Julieann Vose1, Jared Jaffey2, Camille Akin1
1Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, USA.
轻度超胃肠血症发生在患有原发性甲状腺功能障碍症 (PHPT) 的狗身上,但它与胃肠道症状或水平无关. 对PHPT的治疗不会改变胃素度.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 内分泌学 在内分泌学.
- 狗的健康 狗的健康
背景情况:
- 超血症与人类的超胃肠血症有关.
- 甲状腺功能过高可能导致主要甲状腺功能过高症 (PHPT) 的狗的胃肠道症状.
研究的目的:
- 确定PHPT的狗是否发生高胃血症.
- 评估电离 (iCa),副甲状腺激素 (PTH) 和血清胃素之间的相关性.
- 评估PHPT管理后胃素度是否下降.
主要方法:
- 研究了151只在诊断时接受PHPT的狗和24只接受治疗的狗.
- 不包括患有亚血症,并发疾病或服用酸性抑制剂的狗.
- 在治疗前和治疗后测量血清胃素,iCa和PTH.
主要成果:
- 17.9%的PHPT犬的胃素水平升高;度与iCa或PTH无关.
- PHPT治疗减少了PTH和iCa,但没有显著改变胃素水平.
- 在有或没有胃肠道征兆的狗之间,高胃肠病的患病率没有差异.
结论:
- 在患有PHPT的狗中,可能会发生轻度的高胃血症.
- 这一发现独立于胃肠道征兆.
- PHPT管理不会影响胃素度.
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