在成年人中评估Turkovac疫苗的局部和全身副作用
Bülent Nuri Kalayci1, Doğu Karahan2
1Department of Dermatology, Faculty of Medicine, Malatya Turgut Özal University, Malatya, Turkiye.
Turkish journal of medical sciences
|November 30, 2023
概括
土尔科瓦克疫苗是一种非活化COVID-19疫苗,表现出一般耐受性,并具有轻微的副作用,如注射部位疼痛. 年龄较小,女性性别和慢性疾病等因素与副作用风险增加有关.
科学领域:
- 免疫学 免疫学 免疫学
- 疫苗学 疫苗学 疫苗学
- 公共卫生 公共卫生
背景情况:
- 随着COVID-19的流行,疫苗的快速开发变得必不可少,导致了包括非活化疫苗在内的各种疫苗类型.
- 图尔科瓦克 (Turkovac) 是一个在土耳其开发的非活化COVID-19疫苗.
- 调查Turkovac的安全概况对于其公共卫生实施至关重要.
研究的目的:
- 评估Turkovac COVID-19疫苗的局部和全身副作用.
- 为了确定与Turkovac疫苗副作用相关的人口和临床因素.
主要方法:
- 针对403名18岁以上,接种Turkovac.疫苗的参与者进行了一项横截面调查.
- 通过54个关于疫苗接种后副作用和人口统计数据的多选题问卷收集的数据.
- 研究期:2022年3月至6月,在马拉提亚图尔古特奥扎尔大学研究和培训医院.
主要成果:
- 最常见的局部副作用是注射部位疼痛 (22.8%).
- 常见的全身副作用包括疲劳 (4.2%),肌肉/关节疼痛 (2%) 和头痛 (1.7%).
- 年龄较小 (<47岁),女性性别,慢性病和定期服用药物与更高的副作用发生率有关.
结论:
- 图尔科瓦克 (Turkovac) 药物一般耐受性良好,具有良好的安全性.
- 观察到轻微的副作用,主要是在接种疫苗后24小时内.
- 需要进一步的研究来评估Turkovac在不同人群中的安全性.
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