在非甲状腺疾病综合征期间进行甲状腺功能测试,以及急性病犬的康复
Timothy A Bolton1, David L Panciera1, Caylie D Voudren1
1Department of Small Animal Clinical Sciences, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Tech University, Blacksburg, Virginia, USA.
Journal of veterinary internal medicine
|November 30, 2023
概括
狗的非甲状腺疾病综合征 (NTIS) 会导致甲状腺功能测试中的暂时异常. 甲状腺激素水平通常在急性疾病恢复后4周内恢复正常.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 内分泌学 在内分泌学.
- 内部医学 内部医学
背景情况:
- 非甲状腺疾病综合征 (NTIS) 可以导致甲状腺功能测试结果模仿犬类甲状腺功能低下症.
- 狗的NTIS诱导的甲状腺变化的持续时间和解决方案没有得到充分的证据.
研究的目的:
- 在NTIS和狗的恢复期间记录甲状腺功能测试的变化.
- 为了确定甲状腺功能的正常化所需的时间,在狗的急性疾病后测试正常化.
主要方法:
- 一项前性观察性研究分析了25只患有急性,可治愈疾病且在入院时血清总甲状腺素 (TT4) 含量低的甲状腺功能良好的狗.
- 血清TT4是在入院时和每天测量,直到出院. 在出院后2周和4周收集样本.
- 测量了TT4,自由甲状腺素 (fT4),总3,5,3'-三甲状腺素 (TT3) 和甲状腺刺激激素 (TSH) 的血清度.
主要成果:
- 在入院时,100%的狗患有低TT4,80%患有低TT3,16%患有低FT4.
- 在出院4周后,所有测量的甲状腺激素度 (TT4,ft4,TT3) 都在参考区间内.
- 甲状腺刺激激素 (TSH) 水平在住院和出院时处于参考区间内,在出院后的2周和4周略高于参考区间.
结论:
- 狗中自然发生的NTIS在急性疾病和康复期间诱导甲状腺功能测试的显著变化.
- 对患病狗的甲状腺功能的准确评估可能需要在出院后2-4周测量血清TT4或急性疾病期间测量血清FT4.
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