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Magnetic Resonance Imaging01:24

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging
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身体成像中癌症微结构评估的先进扩散权重MRI及其与组织学的关系.

Ella Fokkinga1,2, Juan A Hernandez-Tamames3,4, Andrada Ianus5

  • 1Biomedical Engineering, Track Medical Physics, Delft University of Technology, Delft, The Netherlands.

Journal of magnetic resonance imaging : JMRI
|November 30, 2023
PubMed
概括

先进的扩散权重核磁共振 (DW-MRI) 技术提供了在身体成像中绘制癌症微观结构的新方法. 这些方法在组织学上得到了验证,有望在瘤学中开发新的生物标志物.

关键词:
身体身体身体身体身体身体身体身体癌症 癌症 癌症 癌症 癌症扩散权重磁共振成像技术的扩散权重磁共振成像组织学 组织学微观结构的微观结构

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科学领域:

  • 生物医学成像技术 生物医学成像技术
  • 在瘤学瘤学.
  • 磁共振成像是一种磁共振成像技术.

背景情况:

  • 扩散权重磁共振成像 (DW-MRI) 传统上专注于大脑应用.
  • 在体像瘤学中,对新型生物标志物的需求越来越大.
  • 先进的DW-MRI方法为组织微观结构分析提供了对组织学的高保真性.

研究的目的:

  • 审查DW-MRI在身体成像瘤学的最新进展.
  • 分析DW-MRI技术与局部组织学相比的价值.
  • 评估新兴DW-MRI方法的组织学有效性.

主要方法:

  • 在体内瘤学中对DW-MRI进行临床前,临床和体内/体外研究的审查.
  • 对采集协议,信号模型,安装设置和微观结构参数的分析.
  • 与参考组织学测量的DW-MRI衍生指数的比较.

主要成果:

  • 热门的技术包括intravoxel不连贯运动 (IVIM),扩散曲解成像 (DKI),VERDICT和IMPULSED.
  • 经过审查的方法提供了癌症微观结构的组织学上有意义的指数 (例如,血管化,细胞性).
  • 虽然这些指数并不总是从数值上准确,但它们显示出对微观病理过程的敏感性.

结论:

  • 对于身体成像瘤学,DW-MRI技术正在进步,提供了与组织学相关的微观结构信息.
  • 证明组织学有效性对于临床采用新的DW-MRI方法至关重要.
  • 未来的研究应该专注于提高扫描仪的稳定性和扩大组织学验证.