在需要机械通风的老年患者中预测呼吸机相关的肺炎,通过气管吸气体的检测
Dan Wang1, Peng Zhao2, Yan-Xin Liu1
1Department of Respiratory and Critical Care Medicine, Second Medical Center of Chinese PLA General Hospital, Beijing, China.
Postgraduate medicine
|November 30, 2023
概括
在老年患者中,早期诊断呼吸器相关肺炎 (VAP) 通过测量气管吸血酶α-amylase (AM),素和脂质负载巨体指数 (LLMI) 得到改善. 组合生物标志物在VAP检测方面具有很高的准确性.
科学领域:
- 关键护理医学 关键护理医学
- 肺部病理学 肺部病理学
- 生物标志物发现发现
背景情况:
- 呼吸机相关肺炎 (VAP) 对机械呼吸系统的老年患者构成重大风险.
- 早期和准确的VAP诊断对于及时干预和改善患者结果至关重要.
研究的目的:
- 评估气管吸收物α-amylase (AM),pepsin和脂载巨指数 (LLMI) 在老年患者中早期诊断VAP的临床实用性.
- 评估这些生物标志物单独和组合的诊断性能.
主要方法:
- 气管吸管样本从老年患者收集,在输管术后96小时内使用机械通风.
- 测量了AM,素和LLMI的水平,并分析了它们的诊断潜力.
- 使用接收器操作特征 (ROC) 曲线分析来确定灵敏度,特异性和切断值.
主要成果:
- 与没有VAP的患者相比,VAP患者的AM,素和LLMI水平显著更高 (P<0.001).
- 联合使用AM,素和LLMI表明ROC曲线 (AUC) 下的高面积为0.905,灵敏度为0.9211和特异性为0.9332.
- 预化前吸收风险因素,MDR细菌和高生物标志物水平被确定为VAP的风险因素.
结论:
- 气管吸附AM,素和LLMI显示出有前途的临床实用性,作为老年人机械通风患者中VAP的早期预警生物标志物.
- 这些生物标志物的综合评估为早期VAP诊断提供了可靠的方法.
更多相关视频
相关概念视频
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen
622
Oxygen therapy is a pivotal aspect of medical care, particularly for patients with respiratory ailments. Two prominent oxygen-delivering systems include the Venturi mask and the transtracheal oxygen catheter.
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
622
Pneumonia V: Nursing management and Prevention
2.1K
Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
2.1K
Pneumonia I: Introduction
245
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
245
Pneumonia III: Complications and Assessment
239
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
239
Tracheostomy Suctioning I: Pre-Procedural Steps
581
Tracheostomy suctioning is a critical procedure healthcare professionals perform to maintain a patent airway in patients with a tracheostomy tube. This procedure is necessary when secretions accumulate in the airway, causing respiratory distress. Here is a step-wise procedural guide for performing tracheostomy suctioning using an open system.
Equipment Required
First, gather all necessary equipment: a sterile suction catheter, a sterile disposable container, sterile gloves, a towel or...
Equipment Required
First, gather all necessary equipment: a sterile suction catheter, a sterile disposable container, sterile gloves, a towel or...
581
Physical Assessment of the Respiratory Tract I: Health History
226
Physical assessment of the respiratory tract is critical to patient care. It allows healthcare professionals to identify and manage various respiratory conditions. The process involves a combination of subjective and objective data collection.
Subjective Data
Subjective data provides vital information about the patient's health history and symptoms. This data is typically collected through interviews in which patients describe their experiences, symptoms, and concerns.
Health history and...
Subjective Data
Subjective data provides vital information about the patient's health history and symptoms. This data is typically collected through interviews in which patients describe their experiences, symptoms, and concerns.
Health history and...
226


