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Updated: Jul 9, 2025

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对Ig超级家族的补充受体的新见解来自两种突变体的结构和功能研究

Huiquan Duan1, Troy G Abram1, Ana Rita Cruz2

  • 1Department of Biochemistry and Molecular Biophysics, Kansas State University; Manhattan, KS.

ImmunoHorizons
|November 30, 2023
PubMed
概括

补充Ig超级家族的补充受体 (CRIg) 结合了补充C3片段,并抑制了替代途径. 突变者表现出较低的亲和力,但可以被设计为增强的抑制功能.

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