女性和男性血液体积和总血红蛋白质量的决定因素和参考值
Laura Oberholzer1, David Montero2, Paul Robach3
1Department of Physical Performance, Norwegian School of Sport Sciences, Oslo, Norway.
American journal of hematology
|November 30, 2023
概括
将血液体积 (BV) 和血红蛋白质量 (Hb质量) 正常化为瘦体质量 (LBM),可以减少与性别和健康相关的差异. 脊髓瘤是BV和Hb质量的强有力的预测因素,表明其临床实用性.
科学领域:
- 身体生理学 身体生理学
- 临床医学 临床医学
- 身体组成分析 身体成分分析
背景情况:
- 血液体积 (BV) 是一个关键的临床指标,通常表达为每公斤体重 (BM).
- 脂肪质量增加可能导致低估BV,当正常化到BM,特别是在不同的人群中.
- 了解性别,年龄和健康等因素如何影响BV,需要适当的规范化方法.
研究的目的:
- 调查将BV和血红蛋白质量 (Hb质量) 归正为瘦体质量 (LBM) 是否会减少使用体质量 (BM) 时观察到的差异.
- 评估性别,年龄和运动状况对BV和Hb质量的影响,当LBM与BM相比正常化时.
- 在人体组成参数中,确定BV和Hb质量的最重要的预测因子.
主要方法:
- 血液体积 (BV),血红蛋白质量 (Hb质量),身体成分 (包括LBM和BM) 和心肺呼吸能力的分析.
- 包括263名女性和319名男性,年龄在10-93岁之间,BMI在14-41公斤/米之间.
- 比较BV和Hb质量正常化到BM和LBM,包括107名运动员的队列.
主要成果:
- 女性的BV/BM比男性低25%,但女性的BV/LBM比男性高6%.
- 在女性中,Hb质量/BM低34%,而Hb质量/LBM仅有6%的差异.
- 运动员表现出比BV/BM高17.2%,当LBM正常化时降至2.5%;LBM是BV和Hb质量的最强预测因素.
结论:
- 将血量和血红蛋白质量正常化为瘦体质量有效地减少基于性别的差异.
- 瘦体质量是血液体积和血红蛋白质量与总体质量相比的优越参考值.
- 血红蛋白质量正常化为瘦体质量 (Hb质量/LBM) 为管理血液平衡提供了有价值的临床指标.
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