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假阳性和假阴性对比增强型乳房造影:改善癌症检测的陷和策略

Molly B Carnahan¹, Laura Harper¹, Parker J Brown¹

¹From the Department of Radiology, Mayo Clinic Arizona, 5777 E Mayo Blvd, Phoenix, AZ 85054 (M.B.C., L.H., P.J.B., S.E., R.E.S., B.K.P.); and Department of Radiology, Mayo Clinic Rochester, Rochester, Minn (A.A.B.).

Radiographics : a review publication of the Radiological Society of North America, Inc

|November 30, 2023

概括

增强对比度的乳腺造影 (CEM) 通过将标准乳腺造影与对比度成像相结合,提高了乳腺癌的检测. 了解虚假阳性和负性的原因是改进该技术以获得更好的准确性的关键.

科学领域:

放射学放射学是一门学科.
医疗成像医学成像
在瘤学瘤学.

背景情况:

增强对比度的乳房显微镜 (CEM) 是一种新兴的乳房成像技术.
它将结构性乳房扫描数据与瘤新血管性的功能信息相结合.

研究的目的:

审查CEM中虚假阳性和虚假阴性发现的原因.
讨论减少CEM诊断错误的策略.

主要方法:

对CEM现有的文献和临床经验的审查.
分析导致虚假阳性 (例如,良性血管病变,文物) 和虚假阴性 (例如,隐蔽的病变,技术问题) 的因素.

主要成果:

CEM显示的准确性与MRI相当,具有潜在的更高的特异性.
虚假阳性的常见原因包括血管良性病变和人工物.
假阴性可能是由于可视化不良,背景辅酶增强或技术/感知错误造成的.

结论:

尽量减少虚假阳性和负性的策略对于优化CEM至关重要.
最近的进展包括CEM引导的活检能力.
需要进一步的大规模研究来验证CEM的性能.

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