相关实验视频

Updated: Jul 9, 2025

Identifying PD-1/PD-L1 Inhibitors with Surface Plasmon Resonance Technology
07:04

Identifying PD-1/PD-L1 Inhibitors with Surface Plasmon Resonance Technology

Published on: May 2, 2025

328

在使用深度学习模型的PD-L1对手的自抑制域的基进化

Odessa J Goudy1, Amrita Nallathambi1, Tomoaki Kinjo1

  • 1Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill, NC 27599.

Proceedings of the National Academy of Sciences of the United States of America
|November 30, 2023
PubMed
概括

研究人员利用深度学习 (DL) 为癌症治疗设计了高亲和度蛋白质结合剂. 这种计算方法快速设计了自抑制域 (AiDs),在瘤环境中条件激活PD-L1对手.

关键词:
在PD-L1中.计算型蛋白质设计一个新的蛋白质设计.深度学习是一种深度学习.蛋白质蛋白质相互作用

更多相关视频

Author Spotlight: Magnetic Fluorescent Bead-Based Dual-Reporter Flow Analysis of PDL1-Vaxx Peptide Vaccine-Induced Antibody Blockade of the PD-1/PD-L1 Interaction10:18

Author Spotlight: Magnetic Fluorescent Bead-Based Dual-Reporter Flow Analysis of PDL1-Vaxx Peptide Vaccine-Induced Antibody Blockade of the PD-1/PD-L1 Interaction

Published on: July 7, 2023

1.3K
Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches09:47

Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches

Published on: December 15, 2023

1.1K

相关概念视频

EPS and iPS Cells in Disease Research01:21

EPS and iPS Cells in Disease Research

Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...
2.8K