对ARID1A突变卵巢清细胞癌无关的SMARCA4损失:一个病例报告
Samantha Kay Wagner1, Ashley S Moon2, Brooke E Howitt3
1Department of Obstetrics & Gynecology, Stanford University, Stanford, CA, USA.
Gynecologic oncology reports
|November 30, 2023
概括
具有ARID1A突变和SMARCA4损失的卵巢透明细胞癌没有恶化. 复发性瘤恢复了SMARCA4的表达,这表明SWI/SNF复合体在卵巢癌中的适应性.
科学领域:
- 在瘤学瘤学.
- 分子生物学分子生物学
- 遗传学 是一个遗传学.
背景情况:
- 清细胞癌是一种罕见的卵巢癌亚型.
- ARID1A突变是卵巢清细胞癌发展的早期事件.
- SMARCA4 损失与侵袭性妇科癌症有关.
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