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Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation
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抵消低亲和碳水化合物与共价性结合,以激活糖特异性蛋白质用于瘤免疫近距离诱导

Benjamin P M Lake1, Anthony F Rullo1

  • 1Department of Medicine, McMaster Immunology Research Center, Center for Discovery in Cancer Research, Department of Biochemistry and Biomedical Sciences, and Department of Chemistry and Chemical Biology, McMaster University, 1280 Main Street West, Hamilton Ontario, Canada.

ACS central science
|November 30, 2023
PubMed
概括

小分子现在可以参与癌症免疫治疗的低亲和碳水化合物结合受体. 协同参与,而不仅仅是结合,是瘤免疫接近和瘤杀伤功能的关键,克服了较大的治疗方法的局限性.

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