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Updated: Jul 9, 2025

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
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一种新的染色体重塑复杂变体,dcPBAF,参与维持在分化神经元中的转录

Nataliya V Soshnikova1,2,3, Asya M Azieva3,4, Nataliya S Klimenko5

  • 1Department of Transcription Factors, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.

Frontiers in cell and developmental biology
|November 30, 2023
PubMed
概括

研究人员在分化神经元中发现了一种新的聚菌相关BAF (PBAF) 复杂变体,dcPBAF. 这种复合体,具有PHF10异型,缺乏BRD7,对于维持成熟神经元中的高基因转录至关重要.

关键词:
在PBAF复合体中,PBAF复合体PHF10 的异构体.在 PHF10A 中.在 PHF10D 中.染色体重塑 染色体重塑的方法dcPBAF 的意思是双 PHD 指的域名.神经元分化神经元的分化

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