致病性细菌和抗微生物药物耐药性的分布在微生物的整形手术后
Jintian Hu1, Qi Chen2, Fengli Jiang3
1From the Department of Cosmetic Injection Center, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Plastic and reconstructive surgery. Global open
|November 30, 2023
概括
格拉姆阳性细菌,特别是金黄色葡萄球菌,是微小手术后感染的主要原因. 抗菌素耐药性模式各不相同,晚期感染最为常见.
科学领域:
- 整形外科 整形外科 整形外科
- 微生物学 微生物学
- 传染性疾病 传染性疾病
背景情况:
- 微型耳朵是一种先天性耳朵形,通常用手术重建或假肢来治疗.
- 手术后感染是微病的手术纠正后的潜在并发症.
研究的目的:
- 为了识别和表征微生物菌株,导致微手术后的感染.
- 分析这些病原体的体外抗菌耐药性模式.
- 为了将感染特征与外科手术技术和临床细节相关联.
主要方法:
- 在2011年至2021年期间,从261名微型病患者中收集和识别微生物菌株的前景收集和识别.
- 在使用WHONET 5.6和CLSI M100指南进行体外抗菌敏感性测试.
- 收集有关手术程序,感染持续时间和临床结果的数据.
主要成果:
- 格拉姆阳性细菌占主导地位,黄金葡萄球菌 (140/235) 和凝结酶阴性葡萄球菌 (84/235) 是最常见的.
- 格拉姆阴性细菌包括Enterobacter (11/26) 和Pseudomonas aeruginosa (7/26). 这两种细菌是最常见的.
- 黄金葡萄球菌对科特里莫克萨,莱沃素,万科米辛,氨基醇和线索利德表现出高度敏感;凝结酶阴性葡萄球菌对万科米辛和线索利德敏感. 这两种药物都对青素和红红素有耐药性. 感染主要发生在术后晚期,在24548次手术中,整体感染率为1.06%.
结论:
- 格拉姆阳性细菌是微手术后感染的主要病原体.
- 细菌物种,抗菌素耐药性概况和感染持续时间因手术方法而异.
- 了解这些模式对于在微病重建中有效管理术后感染至关重要.
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