药物调和在中国医院的有效性:试点随机对照试验
Dongyan Chai1,2, Zhihui Liu3, Liuyi Wang3
1Department of Pharmacy, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Henan University People's Hospital, Zhengzhou, Henan People's Republic of China.
Journal of multidisciplinary healthcare
|November 30, 2023
概括
这项试点研究比较了药物调和 (MR) 工作流程. 一个新的MR过程比世卫组织推的方法更快,这表明未来试验的可行性.
科学领域:
- 药理学 药理学是指药理学的学科.
- 医疗保健服务研究 医疗服务研究
背景情况:
- 药物调和 (MR) 的实施面临挑战,原因是指导方针的多样化.
- 中国的MR过程与世界卫生组织 (WHO) 的建议有所不同.
- 进行了一项试点研究,以为未来的随机对照试验 (RCT) 提供有关MR工作流程有效性的信息.
研究的目的:
- 为了评估两个不同的药物调和工作流程的有效性.
- 为了比较一种新型MR工艺与世卫组织推的MR工艺.
- 评估一个更大的多中心RCT的可行性.
主要方法:
- 140名患有高血压,糖尿病或冠心病的成年患者被随机分组.
- 干预组:药剂师在与患者沟通之前审查电子记录.
- 控制组:药剂师在入院时与患者进行沟通.
主要成果:
- 研究小组的MRI工作流节省了每个患者平均7分钟 (p=0.004).
- 两组之间无意中服用药物的差异没有显著差异 (p=0.33).
- 在两组中,医生接受度都很高 (87.5%对92.3%,p=0.87).
结论:
- 新的MR工作流显示了效率的提高.
- 在48小时内设置MR实施是可行的.
- 有必要进行多中心RCT以确定MR的有效性.
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