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帕金森病中铁亡的研究进展:一个图书统计和视觉分析

Yangguang Lu¹, Yiqun Chen¹, Zihan Jiang²

¹The First School of Medicine, School of Information and Engineering, Wenzhou Medical University, Wenzhou, China.

Frontiers in aging neuroscience

|November 30, 2023

概括

这项研究分析了关于铁亡和帕金森病 (PD) 的研究,揭示了出版物的快速增长. 关键的研究领域包括铁灭机制,免疫疗法,预后和PD中的瘤微环境.

科学领域:

神经科学是一个神经科学.
生物医学科学生物医学科学
细胞生物学细胞生物学

背景情况:

铁,以铁沉积和脂质过氧化为特征,越来越多地与帕金森病 (PD) 相关.
在PD患者的大脑中观察到铁代谢和氧化损伤的异常.
了解铁亡的作用对于PD研究至关重要.

研究的目的:

为了对连接铁亡和帕金森病的研究进行图书统计分析.
确定这一跨学科领域的关键趋势,有影响力的出版物和研究热点.

主要方法:

从科学网络核心集合 (2012-2022) 中对414篇文章进行了文献计量分析.
使用R软件包"bibliometrix"进行数据可视化和统计分析.
检查的出版物输出,国家,机构,作者,期刊和关键词.

主要成果:

在铁和PD的研究中,年增长率显著 (63.44%).
中国,美国和澳大利亚在出版物方面处于领先地位.
上海通大学和墨尔本大学是非常活跃的机构.
自由激进生物学和医学是最有影响力的期刊.
高频关键词包括"铁","免疫疗法"",预后"和"微环境".

结论:

这项文献计量研究提供了对帕金森病中铁死研究当前情景和未来方向的见解.
识别的关键词突出了研究的活跃领域,包括治疗策略和疾病机制.
这些发现强调了铁灭在理解和潜在治疗PD方面日益重要的重要性.

关键词:

帕金森病是帕金森病的一种疾病.文献计量数据库 (bibliometrics) 是一个生物医学研究是生物医学研究.铁性化 (ferroptosis) 是一种铁依赖细胞死亡的细胞死亡.

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