在内镜鼻腔外科手术后浸泡布托芬醇的鼻包装的影响:一项双盲,随机,安慰剂控制的试验
Jiamei He1, Qingyu Xiao1, Yu Shuai2
1The First Affiliated Hospital of Shantou University Medical College, Department of Anesthesiology, Shantou City, Guangdong Province, China.
Brazilian journal of otorhinolaryngology
|November 30, 2023
概括
在内镜鼻腔手术后,浸泡在丁醇中的鼻包有效减少疼痛,改善睡眠质量. 建议0.03mg/kg的剂量用于临床使用,而不会增加不良影响.
科学领域:
- 麻醉学 麻醉学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 在双边内镜鼻腔手术后,术后疼痛和睡眠障碍很常见.
- 有效的疼痛管理和改善睡眠质量对于患者的康复至关重要.
研究的目的:
- 评估浸泡在布托尔法诺的鼻包装在治疗术后疼痛和改善睡眠质量的有效性.
- 为了确定本应用程序的玻尿酸醇的最佳度.
主要方法:
- 一项随机对照试验,涉及66名接受双边内镜鼻腔手术的患者.
- 患者被分配到三个组:布托尔法醇0.03mg/kg,布托尔法醇0.04mg/kg,或对照组.
- 用视觉模拟量表 (VAS) 评估疼痛,用主观睡眠质量值 (SSQV) 衡量睡眠质量.
主要成果:
- 与对照组相比,甲醇组在手术后8小时,24小时和48小时显示出明显较低的VAS得分.
- 睡眠质量 (SSQV) 在第一个和第二个晚上明显改善了butorphanol组.
- 在两个布托尔法诺度之间,没有观察到疼痛评分或睡眠质量的显著差异. 副作用的发生率在所有组中都是相似的.
结论:
- 浸泡在布托芬醇的鼻包装在减少术后疼痛和改善双边内镜鼻腔手术后的睡眠质量方面非常有效.
- 0.03mg/kg的布托芬醇度似乎足以用于临床应用,在没有增加不良事件的情况下提供好处.
更多相关视频
07:43Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
18.9K
15:04Modeling and Simulations of Olfactory Drug Delivery with Passive and Active Controls of Nasally Inhaled Pharmaceutical Aerosols
Published on: May 20, 2016
11.0K
相关概念视频
Epistaxis
171
Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
171
Suctioning the Nasopharyngeal Airway
445
Nasopharyngeal suctioning is a procedure to remove secretions from the upper part of the respiratory tract that the patient cannot clear independently. It helps maintain airway patency and prevents complications such as aspiration pneumonia.
Equipment Required
Equipment Required
445
