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在急性髓性白血病的老年评估

Justin D Woods¹, Heidi D Klepin¹

¹Section on Hematology and Oncology, Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Winston Salem, North Carolina, USA.

Acta haematologica

|November 30, 2023

概括

老年评估 (GA) 有助于为老年人量身定制急性髓性白血病 (AML) 治疗方法. GA确定了治疗的适应性,改善了治疗结果,并避免了AML患者的过度或不足治疗.

科学领域:

血液学血液学血液学
老年病的医生老年病的医生
在瘤学瘤学.

背景情况:

急性髓性白血病 (AML) 主要影响具有不同健康状况的老年人.
目前老年人AML的治疗策略各不相同,但由于疾病生物学和治疗耐受性,结果仍然不理想.
在AML治疗决策中仅仅依赖时间的年龄,就可能导致不适当的护理.

研究的目的:

审查证据支持使用老年评估 (GA) 在老年人与AML.
讨论GA对临床实践和AML管理的未来研究的影响.

主要方法:

老年评估 (GA) 涉及验证的工具来评估身体功能,并发症,认知,营养,心理健康和社会支持.
关于GA在接受AML治疗的老年人中可行性和影响的现有文献的审查.

主要成果:

在开始AML治疗的老年人中执行GA是可行的.
GA测量,特别是那些评估身体功能,认知和情绪的测量,与AML患者的死亡率和毒性相关.
GA可以帮助优化老年AML患者的治疗决策和临床试验设计.

结论:

老年人的评估是评估AML老年人的健康状况的一个有价值的工具.
将GA整合到临床实践中可以改善AML的治疗个性化和患者结果.
需要进一步的研究,以充分利用GA来增强AML治疗策略.

关键词:

急性髓性白血病是什么?急性髓性白血病是什么?老年病人的评估.年龄较大的成年人.

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