在遗传性性神经症中的运动障碍
Jose Luiz Pedroso1, Thiago Cardoso Vale2, Julian Letícia de Freitas1
1Universidade Federal de São Paulo, Departamento de Neurologia, São Paulo SP, Brazil.
性偏 (SPG) 可以出现各种运动障碍,包括帕金森症, dystonia,震,肌,和动力不良. 识别这些特定症状可以帮助临床医生诊断SPG亚型.
科学领域:
- 神经学 神经学
- 遗传学 是一个遗传学.
背景情况:
- 遗传性性偏 (SPG) 是一组遗传多样性的疾病,导致逐渐的皮质脊柱管退化.
- 复杂的SPG形式通常包括额外的神经症状,如运动障碍和动力衰竭.
研究的目的:
- 审查和总结与运动障碍和动力不良相关的SPG的临床描述.
- 通过突出特定的神经系统表现来帮助临床医生诊断SPG.
主要方法:
- 进行了叙事文学评论.
- 包括到2022年12月发表的案例报告,案例系列,评论和观察性研究.
主要成果:
- 在SPG7和SPG11中报告了帕金森症.
- 在各种类型的SPG中观察到 dystonia, tremor 和 myoclonus.
- ,有时伴有小脑缩,可以发生在几种SPG形式,特别是SPG4,SPG6,SPG7和SPG11.
结论:
- SPG患者可以表现出各种运动障碍,包括帕金森症, dystonia,震,肌和动力衰竭.
- 特定运动障碍的存在可以作为SPG亚型的关键诊断线索.
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