老年人心脏再同步治疗后的结果
Nawaz Z Safdar1, Stephe Kamalathasan2, Ankit Gupta1
1School of Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, UK.
Age and ageing
|November 30, 2023
概括
老年患者受益于心脏再同步治疗 (CRT) 治疗心力衰竭,表现出类似的症状和功能改善. 尽管共发病率较高,但CRT在老年人群中有效,尽管长期存活率因年龄而异.
科学领域:
- 心脏病学 心脏病学
- 老年医学 老年医学
- 医疗器械 医疗器械
背景情况:
- 患有心力衰竭的老年患者往往没有得到心脏再同步治疗 (CRT) 的治疗.
- 接受CRT的老年患者和年轻患者之间的临床反应,并发症和结局的差异尚未确定.
研究的目的:
- 为了比较临床反应,并发症和心脏再同步治疗 (CRT) 的结果,老年人与年轻的心力衰竭患者.
- 评估CRT在老龄化人口中的有效性和安全性.
主要方法:
- 在2008年3月至2017年7月期间植入CRT设备的574名患者的回顾性队列研究.
- 患者被分为三个年龄组:<70,70-79岁和≥80岁.
- 收集的数据包括并发症,症状和心声回应,心力衰竭住院治疗和全因死亡率.
主要成果:
- 老年患者 (≥80岁) 呈现出更严重的症状和更多的并发症,但在基线时左心室功能相似.
- 并发症是罕见的,老年患者中并不比较常见.
- 年龄没有预测CRT的症状或心声回应;然而,10年生存率在老年人群中明显较低.
结论:
- 与年轻患者相比,心脏再同步治疗 (CRT) 对老年患者的症状和左心室功能提供了类似的好处.
- 尽管伴随性疾病负担较高,医疗治疗不太理想,但CRT在老年心力衰竭患者中有效.
- 这些发现支持在老年人中扩大CRT的使用.
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