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为Mpox复发做准备:加拿大多伦多疫情的监测教训
Herveen Sachdeva1,2, Rita Shahin1,2, Sylvia Ota1
1Toronto Public Health.
The Journal of infectious diseases
|November 30, 2023
概括
多伦多 多伦多 多伦多 多伦多
科学领域:
- 公共卫生 公共卫生
- 传染病流行病学 传染病流行病学
- 病毒爆发调查 病毒爆发调查
背景情况:
- 多伦多在2022年经历了一次重要的mopox疫情,疫苗接种运动后病例下降.
- 2023年初的复苏促使对潜在的无症状或未检测到的本地传播进行了调查.
研究的目的:
- 为了调查2023年多伦多mopox复苏的来源.
- 为了确定未被检测到的本地传播是否推动了复苏.
主要方法:
- 对mopox病例数据和流行病曲线的分析.
- 马博克斯病毒废水监测和全基因组测序.
- 疫苗接种覆盖率的监测.
主要成果:
- 2023年的复发涉及17例病例,与2022年的爆发 (515例) 截然不同.
- 整个基因组测序表明一种新的进口事件,而不是本地传播,作为来源.
- 废水数据与病例时间相关;初始第二剂疫苗接种率较低 (16%).
结论:
- 持续的监测和准备对于管理mopox疫情至关重要.
- 不被检测到的局部传播不太可能是2023年复苏的主要驱动因素.
- 持续推广暴露前疫苗接种对于减少疾病负担至关重要.
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