相关实验视频

Updated: Jul 9, 2025

Analysis of β-Amyloid-induced Abnormalities on Fibrin Clot Structure by Spectroscopy and Scanning Electron Microscopy
06:27

Analysis of β-Amyloid-induced Abnormalities on Fibrin Clot Structure by Spectroscopy and Scanning Electron Microscopy

Published on: November 30, 2018

9.2K

五种相似的安托西亚尼丁分子对Aβ1-42原纤维素表现出明显的破坏性作用和作用机制:一个分子动态模拟研究

Yujie Chen1, Chendi Zhan1, Xuhua Li2

  • 1State Key Laboratory of Surface Physics, Key Laboratory for Computational Physical Sciences (Ministry of Education), Department of Physics, Fudan University, 2005 Songhu Road, Shanghai 200438, China.

International journal of biological macromolecules
|November 30, 2023
PubMed
概括

在水果中发现的天然化合物安托西亚尼丁可以分解与阿尔茨海默病 (AD) 相关的粉样蛋白-β (Aβ) 纤维. 奥兰丁丁和丁在开发新的阿尔茨海默病治疗中表现最有前途.

关键词:
粉样蛋白-β原纤维细胞.它们是安东基亚尼丁素.模拟分子动力学模拟

更多相关视频

A11-positive β-amyloid Oligomer Preparation and Assessment Using Dot Blotting Analysis06:17

A11-positive β-amyloid Oligomer Preparation and Assessment Using Dot Blotting Analysis

Published on: May 22, 2018

11.9K
Visualizing Axonal Growth Cone Collapse and Early Amyloid β Effects in Cultured Mouse Neurons06:23

Visualizing Axonal Growth Cone Collapse and Early Amyloid β Effects in Cultured Mouse Neurons

Published on: October 30, 2018

8.0K

相关概念视频

Amyloid Fibrils03:03

Amyloid Fibrils

Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
Amyloid deposits were observed as early as 1639 in the liver and the spleen.   In 1854, Rudolph Virchow performed iodine staining,...
9.6K