跨导管大动脉置换中的演变范式:来自高容量单中心体验的结果
Giulia Costa1, Cristina Giannini1, Matteo Mazzola1
1Cardiac Thoracic and Vascular Department, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.
The American journal of cardiology
|November 30, 2023
概括
过导管大动脉置换 (TAVR) 程序越来越简单,越来越成功. 精简的TAVR方法,包括使用冠状动脉计算机断层扫描血管学 (CCTA),改善患者的生存率.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 医疗器械技术 医疗器械技术
背景情况:
- 透气管大动脉置换 (TAVR) 指示正在扩展到年轻,风险较低的患者.
- 简化和精简TAVR程序对于更广泛的采用和更好的结果至关重要.
研究的目的:
- 评估程序简化对TAVR结果的影响.
- 评估冠状动脉计算机断层扫描血管学 (CCTA) 作为手术前规划工具的安全性和有效性.
主要方法:
- 预计将在2015年至2020年期间招募771名接受TAVR治疗的患者.
- 将患者划分为时间三角形,以分析程序方法和结果的趋势.
- 术前规划的比较 (CCTA与冠状动脉血管学),手术技巧和临床结果.
主要成果:
- 设备立即成功率显著增加,随着时间的推移,住院时间减少.
- 在CCTA的广泛采用 (大约. 60%) 没有报告的不良事件.
- 与简化TAVR方法相关的1年生存率的提高.
结论:
- TAVR程序表现出一贯的趋势,即精简,提高成功率和更好的1年结果.
- 一个基于CCTA的策略安全地减少了手术前侵入性冠状动脉血管造影的需要.
- 功能能力低下,CAD,功能障碍,输血和PVL等因素与较差的结果有关.
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