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在PAR4诱导的持续性膀疼痛期间,脊椎骨的脊柱蛋白质变化

Shaojing Ye1, Nilesh M Agalave2, Fei Ma1

  • 1Lexington VA Health Care System, Research and Development, Lexington, KY, USA.

Neuroscience letters
|November 30, 2023
PubMed
概括

蛋白酶激活受体-4 (PAR4) 的重复激活会在小鼠中引起持续的膀疼痛. 这项研究发现了显著的脊髓蛋白质变化,包括与神经保护和线粒体相关的改变蛋白质,为膀疼痛提供了潜在的治疗点.

关键词:
金属氨基胺 (Metallothioneins) 是一种金属胺.持续的膀疼痛 持续的膀痛脊髓蛋白质是脊髓中的蛋白质.

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