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Updated: Jul 9, 2025

Differentiation of a Human Neural Stem Cell Line on Three Dimensional Cultures, Analysis of MicroRNA and Putative Target Genes
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Differentiation of a Human Neural Stem Cell Line on Three Dimensional Cultures, Analysis of MicroRNA and Putative Target Genes

Published on: April 12, 2015

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该SPOC蛋白DIDO3和PHF3共同调节基因表达和神经元分化

Johannes Benedum1,2,3,4, Vedran Franke5, Lisa-Marie Appel1,2,3

  • 1Department of Medical Biochemistry, Medical University of Vienna, Max Perutz Labs, Vienna Biocenter, Vienna, Austria.

Nature communications
|November 30, 2023
PubMed
概括

死亡诱导消灭剂3 (DIDO3) 和PHD指蛋白3 (PHF3) 通过形成将RNA聚合酶II结合在一起的复合体来调节转录. 这些类似物在基因表达和神经元分化中具有合作性,对抗性和冗余性作用.

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