血压变化预测急性中风患者没有血栓溶解的不良结果:系统性审查和元分析
Yajing Chen1, Yuxia Ma2,3, Jiangxia Qin1
1Evidence-Based Nursing Centre, School of Nursing, Lanzhou University, Lanzhou, Gansu Province, China.
Journal of neurology
|November 30, 2023
概括
在急性中风患者中,较高的血压变化 (BPV) 与失能和死亡率等不良结果的风险增加有关. 这表明BPV是中风预后的一个重要因素.
科学领域:
- 神经学 神经学
- 心脏病学 心脏病学
- 临床研究 临床研究
背景情况:
- 脑卒中是导致残疾和死亡的主要原因.
- 血压变化 (BPV) 越来越被认为是潜在的中风风险因素.
- 在急性中风患者中,BPV的预后值需要进一步澄清.
研究的目的:
- 系统地审查关于急性中风患者血压变化和预后之间的关联的研究.
- 澄清BPV在预测中风结果中的作用.
主要方法:
- 研究的系统审查和元分析.
- 在Embase,PubMed,Web of Science和Cochrane图书馆搜索到2023年1月1日.
- 包括成人中风患者 (≥18岁) 不论中风类型或治疗 (如血栓溶解).
主要成果:
- 在非血栓溶解患者中,较高的静脉压变化与不良结果 (功能障碍,死亡率,神经系统恶化,复发) 的风险增加相关.
- 扩大腹压血压的变化与较高的死亡率和功能残疾风险有关.
结论:
- 血压变化是急性中风结果的新和临床相关预测因素.
- 需要进一步的研究来标准化BPV测量和定义在急性中风.
- 需要进行更大规模的研究来证实这些发现并指导临床实践.
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