唾液微生物组的变化区分了口腔癌患者对化学放射治疗的反应
Marcell Costa de Medeiros1, Stephanie The2, Emily Bellile2
1Periodontics and Oral Medicine, University of Michigan School of Dentistry, 1011 North University Ave, Room G018, Ann Arbor, MI, 48109-1078, USA.
Microbiome
|December 1, 2023
概括
口腔状细胞癌 (SCC) 治疗改变了唾液微生物群,减少了多样性. 治疗后的唾液DMBT1水平增加并与特定的细菌变化相关,可能作为生物标志物.
科学领域:
- 微生物学 微生物学
- 在瘤学瘤学.
- 基因组学就是基因组学.
背景情况:
- 口腔状细胞癌 (SCC) 与口腔微生物失衡有关.
- 这项研究使用16S rRNA基因测序对SCC患者治疗前后的唾液微生物组变化进行了纵向分析.
- 研究将这些微生物组变化与抗微生物蛋白DMBT1.1.表达相关联.
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