由Campylobacter jejuni引起的脊椎骨髓炎在一个免疫能力强的患者身上
Karina Frahm Kirk1,2, Jeppe Boel3, Hans Linde Nielsen4,5
1Department of Infectious Diseases, Aalborg University Hospital, Aalborg, 9000, Denmark.
坎比洛巴克特 (Campylobacter jejuni) 是导致腹的常见原因,很少会导致脊椎骨质炎. 这一案例突显了这种罕见的全身感染的成功手术和抗生素治疗.
科学领域:
- 传染性疾病 传染性疾病
- 细菌学 细菌学是一门学科.
- 整形外科手术 整形外科手术
背景情况:
- 坎比洛巴克特 (Campylobacter jejuni) 是全球细菌性胃肠炎的主要原因.
- 系统性感染,包括骨髓炎,是罕见的C. jejuni表现.
- 由于C. jejuni造成的脊髓骨质炎非常罕见,之前没有关于从骨活检中培养的报道.
研究的目的:
- 报告一个罕见的Campylobacter jejuni诱导的脊椎骨质炎病例.
- 强调在脊椎骨质炎病例中考虑C. jejuni的重要性,特别是在并发性腹的情况下.
- 要突出成功的管理策略,为这种不常见的条件.
主要方法:
- 一个79岁的男性的案例研究,出现腰部疼痛,发烧和腹.
- 诊断方法包括便PCR,血液培养和脊椎MRI.
- 治疗包括脊髓手术 (脊髓解剖和解压) 和为期四周的梅罗胺疗程,随后是克林达米辛.
主要成果:
- 坎比洛巴克特 spp. 的种类. 在便样本中检测到;在血液和脊椎圆盘培养物中发现了C. jejuni.
- 核磁共振扫描显示了L1/L2的骨髓炎,并出现了外周.
- 患者经历了手术后的快速康复和针对性的抗生素治疗.
结论:
- 脊椎骨髓炎应立即考虑C. jejuni,特别是在腹患者中.
- 由于耐药性增加,抗菌素敏感性测试至关重要.
- 根据敏感性结果量身定制的抗生素治疗方案对于有效治疗至关重要.
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