内分泌干扰化学物质:对实践内科医生的健康影响和影响的主流认可
Leonardo Trasande1,2,3, Robert M Sargis4,5,6
1Department of Pediatrics, NYU Grossman School of Medicine, New York, New York, USA.
Journal of internal medicine
|December 1, 2023
概括
合成化学品,包括内分泌干扰化学品 (EDCs),有助于广泛的疾病和死亡率. 通过行为变化和政府行动减少暴露至关重要,特别是对不成比例地受影响的少数群体来说.
科学领域:
- 环境健康 环境健康
- 毒理学 毒理学 毒理学
- 公共卫生 公共卫生
背景情况:
- 环境中无处不在的合成化学物质与整个生命周期的疾病和残疾有关.
- 内分泌干扰化学物质 (EDC) 导致成人慢性疾病,如代谢,心血管和生殖问题,以及内分泌癌症.
- EDC暴露不成比例地影响低收入和少数群体,加剧了健康差异.
研究的目的:
- 突出合成化学物质,特别是EDC的暴露对健康和经济造成的重大负担.
- 强调EDCs在慢性疾病和死亡率中的作用.
- 倡导行为改变和政府政策,以减轻EDC暴露.
主要方法:
- 审查现有的关于合成化学物质暴露和健康结果的科学文献.
- 对疾病负担和经济生产率损失的分析,归因于特定的化学物质,如甲酸盐.
- 检查特定人群暴露数据和健康差异.
主要成果:
- 每年超过90,000人死亡,每年至少损失390亿美元的美国经济生产力与某些酸盐有关.
- 非西班牙裔黑人和墨西哥裔美国人因EDC的疾病负担不成比例.
- 简单的行为变化和政府监督可以修改暴露.
结论:
- 合成化学品,特别是EDC,对公共健康构成重大威胁,造成大量死亡和经济损失.
- 应对EDC暴露需要采取多方面的方法,包括个人行为变化,医疗保健提供者的指导和积极的政府监管.
- 需要针对高暴露水平的人群进行有针对性的查和干预,例如那些接触过多醇基物质的人群.
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