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基于循环德克斯的纳米海绵作为活性药物成分的有希望的载体

Saranya Jawaharlal1, Selvamuthukumar Subramanian2, Venkatesan Palanivel2

  • 1Department of Biochemistry & Biotechnology, Annamalai University, Annamalai Nagar, Tamil Nadu, India.

Journal of biochemical and molecular toxicology
|December 1, 2023
PubMed
概括

纳米海绵是一种新的纳米技术,通过将药物封装在多孔纳米颗粒中以进行向分发来增强药物输送. 本综述探讨了它们在各种剂量形式中的创造,益处和应用.

关键词:
药物输送是药物输送的过程.药物输送药物输送的时间纳米空洞是纳米空洞.这些是纳米海绵.聚合物是一种聚合物.有孔的粒子是有孔的粒子.

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Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are...
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