在受控的卵巢过度刺激中使用淋巴激素起始剂量的预测模型:审查和进展更新
Xiaoxiao Guo1, Hao Zhan2, Xianghui Zhang1
1Department of Reproductive Medicine, Binzhou Medical University Hospital, Binzhou City, Shandong Province, China.
Human fertility (Cambridge, England)
|December 1, 2023
概括
确定开始性腺激素 (Gn) 剂量对于受控的卵巢高刺激 (COH) 在试管婴儿中至关重要. 研究正在探索人工智能和深度学习,以创建更准确的预测模型,以获得最佳的 Gn 剂量.
科学领域:
- 生殖医学 生殖医学
- 生物技术是生物技术.
- 医疗保健中的人工智能
背景情况:
- 控制的卵巢过度刺激 (COH) 是体外受精-胚胎移植 (IVF-ET) 的基础.
- 淋巴激素 (Gn) 的起始剂量显著影响卵细胞产量,周期取消和怀孕结果.
- 尽量减少卵巢过度刺激综合征 (OHSS) 等并发症是ART的一个关键目标.
研究的目的:
- 突出标准化和准确的Gn初始剂量确定在COH中至关重要的重要性.
- 审查过去二十年来 Gn 起始剂量预测模型的演变.
- 探索人工智能 (AI) 和深度学习在开发未来预测模型方面的潜力.
主要方法:
- 对 Gn 起始剂量预测模型现有研究的综述.
- 在COH中影响Gn剂量选择的因素分析.
- 探索用于预测建模的AI和深度学习方法.
主要成果:
- 个性化的Gn起始剂量对于成功的IVF-ET结果至关重要.
- 之前的研究重点是开发 Gn 剂量的各种预测模型.
- 人工智能和深度学习有望提高这些模型的准确性.
结论:
- 精确的Gn起始剂量选择对于优化辅助生殖技术 (ART) 中的COH协议至关重要.
- 人工智能和深度学习的整合预计将导致更精确,更有效的GN剂量预测模型.
- 未来的研究应该专注于开发和验证人工智能驱动的工具,以实现个性化的 Gn 剂量管理.
更多相关视频
05:42Z-Scores for Assessing Ovarian Reserve in Young Patients Undergoing Fertility Preservation
Published on: October 25, 2024
1.2K
05:32Author Spotlight: Investigating the Relationship Between FSH and Pathophysiological Changes in Perimenopausal Women - Insights from a Mouse Model
Published on: August 11, 2023
1.8K
相关概念视频
Hormonal Control of the Ovarian Cycle
527
The ovarian cycle is meticulously regulated by the hypothalamic-pituitary-gonadal axis. This cycle orchestrates the release of a mature oocyte, essential for reproduction.
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle. At puberty, GnRH secretion increases in both frequency and...
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle. At puberty, GnRH secretion increases in both frequency and...
527
Ovarian Cycle
1.3K
The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle...
1.3K
Hormonal Regulation of the Menstrual Cycle
403
The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
403
