组织工程中的生物力学力量和肩部,部,膝盖和脚关节的再生
Merlin Rajesh Lal Lp1, Devendra K Agrawal1
1Department of Translational Research, College of the Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, California USA.
Journal of biotechnology and biomedicine
|December 1, 2023
概括
关节组织撕裂需要新的治疗方法来完全恢复功能. 组织工程中的生物力学力量,使用生物反应器,显示出再生软骨和肌等组织的希望.
科学领域:
- 再生医学是一种再生医学.
- 生物医学工程 生物医学工程
- 整形外科 整形外科 整形外科
背景情况:
- 关节组织 (肌,带,软骨) 的自我愈合能力有限.
- 退行性疾病和伤害需要先进的治疗来恢复关节功能.
- 目前用于关节修复的手术干预与疾病相关.
研究的目的:
- 审查生物力学力量在组织工程中的应用,用于关节再生.
- 要突出生物反应器在应用这些力量中的作用.
- 讨论特定关节组织的再生,包括旋转,部,膝盖和脚.
主要方法:
- 关于组织工程中的生物机械刺激的当前文献的综述.
- 专注于生物反应器技术,用于应用机械力.
- 分析再生特定关节结构的策略.
主要成果:
- 生物机械刺激是组织工程中的关键策略,用于关节修复.
- 生物反应器对于应用可控的生物力学力量至关重要.
- 生物材料,基础科学和细胞工程方面的进步是最佳生物反应器使用所必需的.
结论:
- 利用生物力学的组织工程为关节再生提供了一个有前途的方法.
- 对生物反应器和相关技术的进一步改进对于临床转化至关重要.
- 肌,带和软骨的有效再生需要综合的方法.
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