什么是癌症综合征? 对其拟议的调解人进行批判性评估
Merijn C F Mulders1, Wouter W de Herder1, Johannes Hofland1
1ENETS Center of Excellence, Section of Endocrinology, Department of Internal Medicine, Erasmus MC & Erasmus MC Cancer Institute, 3015 GD Rotterdam, The Netherlands.
Endocrine reviews
|December 1, 2023
概括
癌症综合征 (CS) 涉及神经内分泌瘤 (NEN). 这篇评论证实了血清的存在.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
背景情况:
- 癌症综合征 (CS) 影响大约20%的神经内分泌瘤 (NEN) 患者.
- 由于NEN发病率上升和生存率提高,慢性和耐火性CS症状越来越普遍.
- 目前对CS病理生理学的理解是不完整的,这阻碍了有效的症状管理.
研究的目的:
- 系统地审查和批判性地评估与癌症综合征 (CS) 相关的荷尔蒙调解物的证据.
- 澄清各种激素在CS病变发生过程中的因果作用.
- 为了指导未来的研究和完善CS的临床描述.
主要方法:
- 系统的文献审查.
- 对CS的荷尔蒙调解剂的证据质量的批判性评估.
- 分析了研究的分析,调查了血清素,塔基基宁,甲基醇胺,组胺,布拉迪基宁,卡利克林,前列腺素和莫提林.
主要成果:
- 对大多数假定的CS调解者的证据很少,质量也很差.
- 足够的证据证实了血清素在CS相关的腹和纤维化中的作用.
- 塔基基宁和甲醇胺被认为是潜在的CS调解物,而对其他物质的证据是不够的.
结论:
- 血清素是癌症性综合征 (CS) 症状,如腹和纤维化的主要证实调解者.
- 塔基基宁和甲基醇胺可能在CS病变发生过程中发挥作用,这需要进一步研究.
- 目前的证据不足以将组胺,布拉迪基宁,卡利克林,前列腺素或莫提林与CS联系起来.
关键词:
布拉迪基尼尼尼尼尼是什么意思癌症性综合征是一种癌症性综合征.类甲基胺 (Catecholamines) 是一种类甲基胺.基因组胺组胺的使用方法血清胺 (serotonin) 是一种神经元.塔奇基尼因的含量是多少更多相关视频
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