相关实验视频

Updated: Jul 9, 2025

The C-seal: A Biofragmentable Drain Protecting the Stapled Colorectal Anastomosis from Leakage

The C-seal: A Biofragmentable Drain Protecting the Stapled Colorectal Anastomosis from Leakage

Published on: November 4, 2010

产生原酶的细菌在结直肠外科手术后的静脉泄漏中很常见:系统性审查

Anders Bech Jørgensen^1,2, Isabella Jonsson³, Lennart Friis-Hansen^4,5,6

¹Department of Surgery, Holbæk Hospital, Part of Copenhagen University Hospitals, Region Zealand, Denmark. dr.bech@gmail.com.

International journal of colorectal disease

|December 1, 2023

概括

产生原酶的肠道细菌在结直肠外科手术后出现解静脉泄漏 (AL) 的患者中更为普遍. 然而,从目前的研究来看,它们在这种并发症中的确切作用仍然不清楚.

科学领域:

胃肠病学和外科手术
微生物学微生物学
临床研究临床研究

背景情况:

肠道细菌可以产生原酶,这些酶会降解肠壁中的原.
这种酶活性可能有助于结直肠外科手术后的解静脉泄漏 (AL) 的病理生理学.

研究的目的:

在结直肠手术后,系统地审查和调查AL患者的原酶产生细菌的频率,与没有AL患者相比.

主要方法:

按照PRISMA和AMSTAR指南进行系统审查,并注册在PROSPERO.
在PubMed,EMBASE,Google Scholar和Cochrane CENTRAL中搜索相关的人类研究的文献.
包括15项与52,945名患者 (1,747名AL患者) 的观察性研究,分析来自各种样本来源的细菌学数据.

主要成果:

在15项涉及AL患者的研究中,在10项中发现了产生原酶的细菌.
没有研究量化了细菌的存在或原酶的产生.
样本材料,分析方法和收集时间存在显著的异质性;DNA测序研究没有报告这些细菌.

结论:

产生原酶的细菌更常见于AL后结肠直肠手术患者中.
在AL中这些特定细菌的临床意义和致病性仍未确定.
需要进一步的研究来阐明个体肠道细菌在解肠道泄漏中的作用.

关键词:

解剖学上的泄漏.细菌原酶是一种细菌的原酶.结肠直肠外科手术是什么意思复杂性复杂性复杂性我们的肠道微生物组.

更多相关视频

Murine Ileocolic Bowel Resection with Primary Anastomosis

Murine Ileocolic Bowel Resection with Primary Anastomosis

Published on: October 29, 2014

Creation of Colonic Anastomosis in Mice

Creation of Colonic Anastomosis in Mice

Published on: January 17, 2019

相关概念视频

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...

Inflammatory Bowel Disease V: Surgical Management

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD: