在右叶发作中,中半球间同步和有效连接受损
Ke Shi1, Lu Yu1, Yiling Wang2
1Department of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
概括
右叶 (TLE) 显示大脑功能网络发生变化,影响认知功能. 这些网络变化,特别是指向功能连接,与右TLE患者的认知障碍有关.
科学领域:
- 神经科学是一个神经科学.
- 认知科学 认知科学
- 医疗成像医学成像
背景情况:
- 大脑功能网络对于认知过程至关重要.
- 认知障碍是叶 (TLE) 的一个常见特征.
- 右TLE (rTLE) 通过网络变化特别影响认知功能.
研究的目的:
- 在rTLE中使用voxel-mirrored homotopic connectivity (VMHC) 调查定向功能连接的变化.
- 探索RTLE中功能连接性改变和认知障碍之间的关联.
主要方法:
- 包括27名rTLE患者和27名健康对照.
- 使用了voxel镜像同位素连接 (VMHC) 和格兰杰因果关系分析 (GCA).
- 进行了GCA结果和认知功能得分之间的相关性分析.
主要成果:
- 在rTLE组中,在双边中额头,中额头,上额头 (SFGdor) 和上边 (SMG) 中观察到VMHC的减少.
- 改变的VMHC区域显示与默认模式,传感器和视觉网络的异常定向连接.
- 认知得分 (MoCA,反应时间) 与特定的定向连接途径相关,特别是涉及MFG,SFGdor,SMG和SMA.
结论:
- 功能性脑网络障碍与RTLE的认知障碍有关.
- 有针对性的功能连接性改变为RTLE认知缺陷的神经生物学基础提供了洞察力.
更多相关视频
09:32Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients
Published on: December 18, 2016
12.4K
09:57Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization
Published on: September 20, 2024
2.7K
相关概念视频
Lateralization
340
Brain lateralization refers to the division of mental processes and functions between the two hemispheres of the brain, a phenomenon that optimizes neural efficiency and underpins complex abilities in humans. This specialization allows each hemisphere to perform tasks where it has a comparative advantage, facilitating more refined cognitive capabilities across different domains.
340
Cerebral Hemispheres
349
The human brain, a complex organ, is functionally divided into two cerebral hemispheres—left and right. These hemispheres are interconnected by a structure of paramount importance, the corpus callosum. This substantial bundle of neural fibers is not just a bridge between the hemispheres but a crucial element for the brain's comprehensive functioning. It enables efficient communication between the two hemispheres, allowing each side of the brain to control and receive sensory and motor...
349
