预后评分系统对非补偿性肝硬化患者的2年生存估计
L C Nguyen1, N M Nguyen, T N Nguyen
1Gastroenterology and Hepatology Center, Bach Mai Hospital, Giai Phong Road, Ha Noi, Vietnam. nguyenconglongbvbm@gmail.com.
European review for medical and pharmacological sciences
|December 1, 2023
概括
RefitMELD评分是预测越南患者肝硬化不补偿2年死亡率的最可靠工具,其表现优于其他预后模型.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 临床预后 临床预后
- 医学统计 医学统计
背景情况:
- 肝硬化患者生存的预后模型需要在不同的人群中进行验证,特别是在越南.
- 对于肝硬化中期生存预测仍然是一个挑战.
研究的目的:
- 评估各种预后评分系统在预测越南肝硬化患者2年死亡率方面的准确性.
- 确定最可靠的模型,以预测这一群体中期存活率.
主要方法:
- 在2019年12月至2021年11月期间,对904名住院肝硬化患者进行了前性研究.
- 计算和比较 Child-Pugh (CP),MELD,MELD-Na,IMELD,Refit MELD 和 Refit MELD-Na 的得分.
- 两年的随访以评估生存结果.
主要成果:
- 已故的患者表现出显著较低的白蛋白和更高的INR,胆红素和肌素水平.
- 与幸存者相比,所有预后得分在非幸存者中显著更高.
- RefitMELD显示死亡率预测的曲线下面面积 (AUC) 是最高的 (0.768).
结论:
- 已故的肝硬化患者呈现显著升高的Child-Pugh和MELD得分.
- RefitMELD评分是越南患者肝硬化不补偿2年死亡率的最准确预测指标.
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