评估心电图的发现和炎症参数在患有良性发性位置性的患者
1Department of Cardiology, Faculty of Medicine, Adıyaman University, Adıyaman, Turkey. sabus@adiyaman.edu.tr.
European review for medical and pharmacological sciences
|December 1, 2023
概括
良性发性位置性 (BPPV) 与心脏电活动的改变有关,由较高的前额QRS-T角度表明. 在BPPV患者中,炎症,特别是中性粒细胞与淋巴细胞比率 (NLR),与这种心脏标志物有很强的相关性.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 临床电生理学 临床电生理学
背景情况:
- 良性发性定位 (BPPV) 是一种普遍存在的前体障碍,导致头和鼻.
- 额头QRS-T (fQRS-T) 角度是一种新的心电图 (ECG) 标记,反映了心室再极化异质性.
- 调查BPPV和心脏电生理学之间的联系可能会揭示更广泛的健康影响.
研究的目的:
- 探索被诊断为BPPV的个体中fQRS-T角度和炎症标志物之间的关系.
- 为了比较BPPV患者和健康对照者的fQRS-T角度和炎症水平.
- 确定炎症标志物是否预测BPPV.中的心脏再极化变化.
主要方法:
- 一组49名BPPV患者和51名健康对照进行了心电图分析.
- 测量了关键的心电图参数,包括fQRS-T角度,QRS持续时间和QT间隔.
- 血液测试评估了炎症标志物:中性粒细胞与淋巴细胞的比率 (NLR),血小板与淋巴细胞的比率 (PLR),单细胞与淋巴细胞的比率 (MLR) 和C反应蛋白与白蛋白的比率 (CAR).
主要成果:
- 与对照组相比,BPPV患者的fQRS-T角度显著更高 (p<.001).
- 在BPPV患者中观察到高水平的NLR,PLR,MLR和CAR (所有患者p<.001).
- 在NLR和fQRS-T角度 (r=.718,p<.001) 之间发现了强烈的正相关性,NLR在回归分析中预测了fQRS-T角度 (p<.001).
结论:
- BPPV与明显改变的心室再极化有关,由增加的fQRS-T角度表明.
- 炎症,特别是NLR,在影响BPPV患者心脏电生理学方面发挥着至关重要的作用.
- 这些发现表明,BPPV可能有系统性影响,影响心脏功能,超出前庭症状.
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