在息护理中的老年患者中,头发皮质醇水平和认知功能的变化
Rosana Ribić1, Tina Košanski2, Marijana Neuberg3
1Associate Professor, University centre Varaždin, University North, Croatia.
International journal of palliative nursing
|December 1, 2023
概括
这项研究发现,在住院3周后,老年息护理患者的头发皮质醇水平显著变化,这表明头发皮质醇是一种有用的压力生物标志物. 在此期间,认知功能没有显著变化.
科学领域:
- 老年学是指老年学的学科.
- 心理神经内分泌学心理学
- 抚慰性护理医学 抚慰性护理医学
背景情况:
- 息治疗患者,特别是老年人,经历了相当大的压力.
- 确定可靠的压力生物标志物对于监测患者健康至关重要.
- 头发皮质醇提供了一个潜在的长期指标的生理压力.
研究的目的:
- 评估老年息护理患者头发皮质醇水平和认知功能的变化.
- 为了确定毛皮质醇是否可以在这个人群中作为有效的压力生物标志物.
- 评估这些参数在基线和住院3周后.
主要方法:
- 采用了一个单心试点研究设计.
- 使用酶相关免疫吸收试验 (ELISA) 测量了头发皮质醇度.
- 认知功能被评估使用迷你精神状态检查2 (MMSE-2):简要版本.
主要成果:
- 在基线和3周随访期间 (p=0.007) 中,平均头发皮质醇水平观察到具有统计学意义的差异.
- 在相同的时间点之间,微型精神状态检查2 (MMSE-2) 的得分没有发现统计学上显著的差异.
- 这些发现表明,在研究期间,生理压力标志物发生了变化,但认知表现没有变化.
结论:
- 在住院期间,老年息护理患者的皮质醇水平发生显著变化.
- 头发皮质醇在这个患者群体中显示出作为压力相关生物标志物的潜力.
- 需要进一步的研究来探索这些发现的临床影响.
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