相关实验视频

Updated: Jul 9, 2025

Detection of Homologous Recombination Intermediates via Proximity Ligation and Quantitative PCR in Saccharomyces cerevisiae
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Published on: September 11, 2022

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酸化三聚体SOSS1复合物和RNA聚合酶II在双链断裂时触发液态-液态相分离

Qilin Long1, Marek Sebesta2, Katerina Sedova2

  • 1Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK.

Cell reports
|December 1, 2023
PubMed
概括

在DNA断裂时,SOSS1复合体与RNA聚合酶II结合,形成液体修复区. 这种相互作用对于有效修复DNA损伤至关重要,特别是以R循环依赖的方式.

关键词:
科普:分子生物学 分子生物学造成的DNA损伤是DNA损伤.DNA:RNA杂交的混合物这就是LLPS.在R-Loop中使用.的RNA聚合酶II.在SOSS1复合体中,c-Abl 激酶酶的作用hSSB1 这是一个很好的例子.阶段分离的阶段分离.酸化的方法是:光化.

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